Shimadzu Instrument Gas chromatography-mass spectrometry GCMS-QP2020 Instrument Introduction

Product Name: Gas chromatography-mass spectrometer GCMS-QP2020

Product information:

High performance chemical organic compound analysis instrument, comprehensively solving ROHS2.0 organic compounds

The monitoring of trace compounds related to environmental pollution/human health, as well as the research and development of high-performance new materials/chemicals, are becoming increasingly important. How to reduce operating costs and protect the Earth's environment by improving the efficiency of routine analysis and reducing power consumption of analytical instruments has become a global issue. In this context, Shimadzu developed GCMS-QP 2020 to meet the requirements of the times. (Comparison value under specified conditions of our company)

The anti pollution high-sensitivity gas chromatography-mass spectrometer GCMS-QP2020 has the following characteristics:

1. Integrate high sensitivity and low experimental cost

Relying on excellent mass spectrometry technology, compatible with multiple carrier gas types (He, H2, N2), and exploring the analytical limits of mass spectrometry technology. No need to replace the ion source, easily switch ionization modes.

(1) High sensitivity

The overall inert high-sensitivity ion source using patented Shield technology and the patented "OD lens technology" combined with a "new low-noise CPU board" effectively reduce matrix interference and electronic noise in complex samples, achieving higher sensitivity of GCMS in the industry (S/N ≥ 2000:1), becoming a powerful tool for trace substance analysis in complex samples. In addition, setting tuning parameters can also be applied to the analysis of high concentration samples. Thus, ideal high-precision analysis results can be easily obtained within a wide dynamic range from low to high.

(2) New ultra efficient large capacity vacuum system

GCMS-QP2020 is equipped with a new "high-capacity and ultra efficient vacuum system" - a turbo molecular pump that uses an ion source (200L/sec) and a quadrupole mass analyzer (200L/sec) for exhaust, achieving a dual inlet differential exhaust volume of up to 400L/sec. At the same time, the compressed gas effect is increased by more than three times, effectively ensuring the best mass spectrometry state under any carrier gas conditions. The super efficient vacuum system supports the following applications in all aspects:

1) Support the simultaneous installation of two chromatography columns of different polarities into a vacuum system to form a 'Twin Line MS Dual Column System'. Effectively reducing the time required to replace chromatography columns in different applications without sacrificing sensitivity, switching between two chromatography columns can be achieved directly through simple software operations.

2) The ultra-high efficiency and large capacity vacuum system ensures a high vacuum degree in the mass spectrometry system, effectively reducing ion source contamination and thus reducing ion emissions

Maintenance operations of the source.

3) Support rapid start-up of the instrument, allowing for actual sample analysis within 30 minutes of startup, improving the stability and accuracy of the instrument

The reliability of the data.

4) The maximum column flow rate can reach 15 mL/min, so it can be connected to a wide caliber capillary column with an inner diameter of 0.53mm to achieve large volume

Analysis with high throughput and high expansion requirements such as injection.

(3) Ultra fast scanning performance (patented ASSPTM technology)

A high-precision all metal quadrupole mass analyzer is adopted, combined with a newly designed high-speed data acquisition and processing platform, which has the fastest scanning speed among similar products (20000 u/sec). When collecting data at high speed, Advanced Scanning Speed Protocol (ASSPTM) patented technology is used to accelerate ion transport, effectively reduce high-quality end discrimination, and minimize the problem of sensitivity decrease and mass spectrum accuracy decrease during high-speed scanning above 10000 u/sec. Compared with traditional methods, the sensitivity is increased by more than 5 times, especially in the application of Fast GCMS, Scan/SIM simultaneous determination FASST mode, GC × GC/MS, which can effectively improve the sensitivity of scanning data and obtain classic mass spectra. MS-QP2020 performs even better in rapid analysis. (Patent: U6610979）

(4) Advanced Electronic Flow Control (AFC) System

Equipped with an advanced electronic flow control system AFC, it can achieve a unique carrier gas constant linear velocity control method (patented technology). During the program heating process, the carrier gas can maintain the same linear velocity, which can keep the column efficiency in the best state and achieve the best experimental results. Using the same chromatographic column and under the same instrument conditions, the gas phase and gas quality can achieve the same retention time.

(5) Advanced Electronic Flow Technology (AFT) System

1) Backblowing function:

When the target compound is detected, the residual substances in the chromatographic column can be discharged from the diversion valve of the injection port by reversing the flow of the carrier gas, which greatly shortens the analysis time, improves the analysis efficiency, and avoids contamination of the chromatographic column, reducing maintenance frequency and cost.

2) Detector diversion function:

It is possible to split the flow path at the end of the capillary column, so as to transport the sample to multiple detectors and ultimately obtain the results of different detectors, achieving the simultaneous acquisition of information from multiple detectors in one injection and greatly improving the analysis efficiency;

3) Detector switching function:

It is possible to switch the flow path 100% at the end of the capillary column, allowing different substances to enter different detectors for analysis, achieving optimal sensitivity;

4) Multi dimensional gas chromatography technology MDGC/GCMS and full two-dimensional gas chromatography technology GCxGC qMS functions:

For complex samples, a single injection can be achieved to switch between different polarity chromatographic columns for separation and analysis, thereby achieving the best separation effect and greatly improving the analytical ability of complex samples;

(6) Dual jet cooling system

Equipped with a "dual jet cooling system", a cooling fan has been added at the air inlet to achieve rapid cooling by optimizing air circulation during cooling. The time required to cool from 450 ℃ to 50 ℃ is less than 3.4 minutes, greatly improving the efficiency of analysis.

(7) Multiple attachments to choose from

We offer a variety of accessory options, such as multifunctional sampler AOC 6000, headspace, purge and capture, direct injection, thermal analysis, thermal cracking, etc., to meet the analysis needs of users in different fields.

1. Intelligent software functions

The GCMS Insight software package provides an integrated analysis process from method creation to data analysis, with intelligent software functions significantly improving analysis efficiency.

(1) Smart SIM Database

Shimadzu Smart SIM database registers optimized method parameters in the database, without the need for complex settings or standard samples, and automatically creates the best instrument analysis method.

(2) Retention time automatic calibration - no need for standard samples, automatically create instrument methods for qualitative analysis!

By using the relative retention time retention index of n-alkanes for calculation, the automatic retention time correction function (AART) can predict the current retention time of the target compound without the need to analyze the standard again when the device is changed or the chromatographic column is truncated. By analyzing the n-alkanes once, the current retention time of the target compound can be inferred. This can simplify the calibration of chromatographic peak retention time after column replacement or maintenance, reducing human error in operation. At the same time, Shimadzu has also developed various method packages and databases based on this feature. Through the Smart SIM function, one click can automatically calculate the current retention time, without the need for standard samples, and automatically create instrument methods for qualitative analysis.

(3) Quick DB Food Pesticide Residue Screening Database - Rapid Screening, Qualitative and Semi Quantitative

In order to quickly respond to food safety emergencies and effectively address pesticide residue analysis in food, the "Quick DB Food Pesticide Residue Screening Database" can be used. Rapid screening of pesticide residues without the need for standard samples, obtaining qualitative and semi quantitative results. The database has pre registered 19 pesticide substitutes as internal standard substances to generate internal standard curves. Qualitative and high-precision semi quantitative screening of 478 components can be carried out without the need for pesticide standards, reducing the cost of using user standards and method development; At the same time, through the Twin Line MS dual column system, it is easy to handle the analysis of complex matrix samples - providing analysis methods for complex matrix samples including processed foods.

(4) Rich database based on retention index provides comprehensive application support

In addition to the general NIST spectrum library and Wiley spectrum library, there are many method packages and databases developed based on retention index, such as Compound Composer rapid screening database, metabolite analysis database, pesticide analysis method package, water quality analysis method package, pesticide spectrum library, essence flavor spectrum library, forensic drug database, EPA analysis software, VOCs analysis software, etc. Support both general spectrum library and self built spectrum library functions, while retaining the similarity retrieval function of the index.

(5) Multiple customized cutting-edge analysis systems lead future laboratory technology

Equipped with distinctive front-end technology, expanding unlimited analytical possibilities. Provide GPC-GCMS, MDGC/GCMS，GCxGC-qMS，

Tailored professional solutions for different configuration methods such as Py Creator System, Off slave Analyzer, TD-GCMS System, etc.

(6) Intelligent data analysis software LabSolutions Insight

LabSolutions Insight is a multi data analysis software that has the function of verifying data validity and evaluating quantitative results of multiple components. Synchronize the display of quantitative information and corresponding chromatograms for all samples. Five colors can be used to customize the range of specified result values, and the result values labeled with different colors can more intuitively display the situation of target substance exceeding the standard and QC results in the sample. When adjusting the standard curve fitting and manually integrating chromatographic peaks, the latest result data is also synchronously output.

(7) AOC-6000 multifunctional automatic sampler+Twin line MS dual column system

The "AOC-6000 Multi functional Automatic Sample Injector+Twin Line MS" analysis system can quickly replace chromatography columns of different polarities for complex food or processed foods, thereby obtaining better peak shapes and qualitative and quantitative results; Automatically and quickly switch between different injection methods (liquid injection, headspace injection, and SPME) and chromatographic columns to meet the efficient switching of different analysis projects based on user analysis needs. At the same time, the AOC 6000 multifunctional automatic sampler can achieve automatic addition of internal standards, automatic configuration of standard curves, and automatic derivatization. It can also meet the automation requirements of more customized analysis programs through editing commands.

(8) Rich qualitative features

1) Quick CI function:

No need to replace the ion source, easily switch ionization modes. The CI ionization method can be used for data collection first, and the molecular weight can be obtained through CI mass spectrometry. Then, when using EI mass spectrometry for retrieval, the pre obtained molecular weight can be input into the search directory position to obtain more accurate qualitative analysis results.

2) The multi retention index function provides high-precision qualitative analysis:

In software workstations, the search scope can be narrowed down by retaining multiple finger arrays and different analysis conditions. Even for isomers with high similarity mass spectra, high-precision qualitative results can be obtained.

(9) Scan/SIM Simultaneous Measurement (FASST)

Simultaneous measurement using Scan/SIM can meet the requirements of high-sensitivity quantitative analysis and qualitative analysis. Two types of data results can be collected and saved simultaneously in one analysis, greatly reducing the data collection time. This measurement mode significantly enhances the analysis efficiency of the laboratory.

(10) COAST function (automatic creation of SIM table)

Automatically create a SIM table based on the compound table obtained from full scanning, allowing users to quickly and conveniently obtain the required reference and quantitative ion information for compound quantification without manual input, greatly improving work efficiency.

(11) Retain Index Retrieval Function (LRI)

The similarity retrieval function using retention index supports dual retrieval of similarity and retention index, narrowing down the range of candidate compounds and simplifying ingredient confirmation. Simply operate the GCMS-QP2020 workstation to perform the retention index retrieval function.

(12) Rich report management functions

The GCMS Insight software equipped with GC-MS standards includes a series of functions, including precise printing based on the displayed spectra on the screen, creating reports using specific template files, etc. After analysis is completed, the analysis report can be easily output in a specific format through simple operations.

(13) Integrated Data Structure Pattern

Adopting the most advanced "integrated data structure mode" control software makes instrument control and data processing easier. The data file records all information related to data collection and analysis, such as instrument conditions, batch tables, qualitative parameters, quantitative parameters, and report files. The tuning results are also saved in the data file, achieving traceability of all information and ensuring high reliability of the data.

(14) Powerful data computing capabilities

Support high-precision control QA/QC function, capable of automatically calculating signal-to-noise ratio and precision

Methodological indicators such as degree, recovery rate, detection limit, instrument system inspection function, and user safety

Full management function.

(15) Supports both Chinese and English software, supporting sample names, file names, and sequence names in full Chinese

Waiting for input.

3. Easy maintenance and unique design

(1) Easy sTop function

The most frequently maintained components in GCMS are the injection port gasket and liner. The "Easy sTop function" of GCMS-QP2020 allows for maintenance of the injection port without the need to turn off the vacuum pump, greatly reducing instrument standby time. After maintenance is completed, the leak check is automatically performed. If no air leakage is detected, the temperature and flow rate will automatically return to the analytical installation conditions. After completing the maintenance of the injection port, the instrument only needs to wait for 10 minutes to turn on and stabilize.

(2) Cleaning ion source and replacing ion source filament

The front opening design of the ion source makes maintenance of the ion source very simple. It can be easily disassembled and installed from the front of the instrument, and is easy to clean and maintain (using a unique high inertness design, the ion source achieves the highest ionization efficiency and has strong anti pollution ability). For example, we no longer need to remove the filament and power supply inside the ion source. We can clean it by simply removing the ion source box.

(3) The ion source adopts a dual filament structure

When one of the filaments is damaged, it automatically switches to the other filament to ensure continued data acquisition. Ensuring the reliability of the data.

(4) High precision metal quadrupole mass analyzer equipped with rotatable pre quadrupole

The rotatable pre quadrupole can effectively prevent contamination of the main quadrupole and subsequent detectors. Even in extreme cases where pollution cannot be cleaned thoroughly, the instrument's state can be quickly restored by rotating the pre quadrupole. This design is not only convenient for maintenance, but also can improve the service life of the quadrupole and reduce maintenance costs.

(5) Standard equipped with Pirani vacuum gauge and ion gauge

It can monitor low and high vacuum levels in real time to avoid safety accidents such as leaks, and also facilitate operation and maintenance.

(6) Support hydrogen and nitrogen as carrier gases

Reducing experimental costs and ensuring safety can be achieved without the need to replace any components.

4. Ecological model design

(1) Ecology Mode

GCMS-QP2020 can switch to the "Ecology Mode" ecological mode during standby, saving instrument power consumption and carrier gas consumption, which helps reduce daily instrument consumption and environmental emissions. Calculated based on working for 6 hours and standby for 18 hours per day, it can save 36% of power consumption compared to traditional models.

Shimadzu's management philosophy is "for the health of humanity and the earth", therefore, we attach great importance to global environmental protection. The instrument adopts an Ecology mode design, which reduces the amount of CO2 emitted from the GCMS production line to only 30% of the previous manufacturing process.

(2) Focusing on Global Climate Change

Shimadzu's management philosophy is "for the health of humanity and the earth", therefore, we attach great importance to global environmental protection. The instrument adopts an Ecology mode design, which reduces the amount of CO2 emitted from the GCMS production line to only 30% of the previous manufacturing process.

5. Compliance with regulations

The GCMS Insight software has security policies, system policies, user permissions and user management, audit tracking, and other functions. While achieving efficient system operation, it fully complies with the requirements of GXP and FDA 21 CFR Part 11 or relevant regulations of the Ministry of Health, Labour and Welfare.