The implantable physiological signal wireless telemetry system is used for long-term measurement of various animals such as conscious and unrestrained rats, mice, rabbits, beagle dogs, monkeys, fish, etcheart rate、Body temperature and activity levelWaiting for physiological parameters. The use of this system can ensure that animals can move freely in the cage without anesthesia or restraint, so that the measured physiological signals can better reflect the physiological conditions of animals in their natural state. Can be used for biological rhythm research and related vital sign monitoring.

The implantable physiological signal wireless telemetry system can wirelessly telemetry and record the heart rate, body temperature, and activity level of experimental animals

The implantable physiological signal wireless telemetry system consists of an implant (E-Mitt), a receiver, cables, and a VitalView recording and analysis computer. The 1-centimeter sized implant E-Mitt integrates sensors, amplifiers, and wireless signal transmitters, with multiple specifications depending on the measurement signal. The implantable E-Mitt repeater does not require a battery and is powered by a receiver. The experimenters buried the implant under the skin of the animal, and physiological signals were collected by the implant and converted into corresponding electrical signals, which were then transmitted wirelessly. The signals were received by the receiver under the feeding cage and transmitted to the data converter. After completing the data conversion, they were sent to the central processor for data processing. The system can connect up to 32 receivers simultaneously to complete large-scale experiments.

An E-Mitt is a miniature device implanted in an animal, which integrates sensors, amplifiers, digital conversion, wireless transmission functions, and solves the problem of anti rejection reactions in living organisms. Implants have specifications for measuring various parameters such as biological heart rate, body temperature, and activity level.

The main features of implantable physiological signal wireless telemetry system are:

Ø Wireless telemetry

Ø The implantable E-Mitt repeater does not have a battery

Long term monitoring - allows continuous and remote telemetry of experimental animals throughout their lives after implantation of the device

Accurate and reliable reporting of physiological and behavioral data of conscious and unrestrained animals

E-MitterMain technical parameters of the implant system:

ER4000 signal receiver
ER4000 signal receiver, used to charge E-Mitters and receive measurement data transmitted back by E-Mitters. Suitable for standard feeding cages for large and small mice.

The signal receiver'sParameters

The excitation receiver and sensor are connected to the computer through VitalView software. Up to 240 data channels can be recorded, with a typical application of 120 test objects. For the E-meter system, a maximum of 32 test objects can be recorded.

VitalView software can set experimental parameters and collect data. Software management connects with hardware and stores basic graphical data analysis for display. The software also provides statistical data display and can output data.

Telemetry - used to monitor temperature, gross motor activity and heart rate data.
Physiological and behavioral monitoring oftransgenic mice and other laboratory animals has never been simpler. Through the use of biotelemetry and a variety of available sensors, it is possible for VitalView to monitor up to seven different physiological or behavioral parameters from a single laboratory subject

Combinations of the following parameters may be monitored for multiple laboratory subjects using VitalView:
Body Core Temperature
Heart Rate
Gross Motor Activity
Running Wheel Turns
Drinking/Licking Frequency
Feeding Behavior
Ambient Temperature
Ambient Light

E-Mitter Battery-Free Implantable Transponders：
Using telemetry to provide temperature, gross motor activity and heart rate data. An E-Mitter is a small implantable transponder that is powered by capturing energy from electrical fields generated by the ER-4000 Energizer/Receiver. This allows the E-Mitter to operate without batteries and remain implanted indefinitely to monitor the subject''s temperature, activity or heart rate. As a result, high costs and downtime of explantation, refurbishment and reimplantation are avoided.

If only the core body temperature of rats and mice needs to be measured, implantable temperature capsules can be selected to remotely measure the body temperature data:

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