Laser Doppler flowmeter is suitable for rapid point or line scanning of various tissues and organs. We can recommend suitable models and configurations based on your research subject and experimental direction. Please call us for consultation.

The LAB model blood flow meter is widely used for measuring blood flow in various organs and tissues, such as cerebral ischemia experiments, skin and muscle blood flow measurement, organ blood flow measurement, skin flap blood flow measurement, gingival pulp measurement, etc.

Model: LAB Single Channel Model

Model: LAB 2ch dual channel model

Main functional characteristics of laser flowmeter：

·Used for measuring cerebral blood flow in rats and mice, as well as measuring blood flow in various tissues and organs;

·Wide testing range, select corresponding probes according to the organization to be tested;

·The probe calibration data is automatically stored in the chip, achieving calibration free and plug and play functionality for the probe;

·The analysis software has powerful functions, automatically generates reports, and provides long-term continuous monitoring;

·Optional multi-channel configuration, capable of measuring multiple parts or animals simultaneously;

·Multiple hosts can be connected to one computer;

Main parameters:

·Used for continuous measurement of tissue blood flow
·Test laser: 780nm semiconductor laser, Class 1M level
·Signal bandwidth: 24HZ-24KHZ
·Time constant: 0.1, 1, 3 sec
·Measurement item: Tissue blood flow: 0-1000.0 (mL/min/100g equivalent), blood flow change curve
·Light intensity analog signal output: 0-10V
·Blood flow simulation signal output: 0-10V
·Fiber optic probe: 100/140 μ m
·Measurement range: within a diameter range of approximately 1mm
·Measurement depth: 0.5mm-1mm
·Working temperature range: 5-40 ℃
·Humidity range: 0-90%

Laser Doppler blood flow has multiple styles and models to choose from, providing: measurement of cerebral blood flow in mice and rats (cerebral ischemia model), measurement of skin and muscle blood flow, measurement of hippocampal blood flow in animals, measurement of skin flap perfusion, measurement of vascular activity research, measurement of gingival blood flow, measurement of blood flow in various tissues and organs (liver, spleen, kidney, etc.), measurement of mesenteric blood flow, measurement of blood flow perfusion in burn wounds; Measurement of tissue oxygen content, measurement of toe end pressure of diabetes foot, etc. Please call us for consultation.

reference:

1. Yamanaka H, Yamaoka T, Mahara A, et al. Tissue-engineered submillimeter-diameter vascular grafts for free flap survival in rat model. Biomaterials. 2018; 179:156-163. doi:10.1016/j.biomaterials.2018.06.022.
2. Liu Y, Mahara A, Kambe Y, et al. Endothelial cell adhesion and blood response to hemocompatible peptide 1 (HCP-1), REDV, and RGD peptide sequences with free N-terminal amino groups immobilized on a biomedical expanded polytetrafluorethylene surface. Biomater Sci. 2021; 9(3):1034-1043. doi:10.1039/d0bm01396j.
3. Nosaka M, Ishida Y, Kimura A, et al. Crucial Involvement of IL-6 in Thrombus Resolution in Mice via Macrophage Recruitment and the Induction of Proteolytic Enzymes. Front Immunol. 2020; 10:3150.doi:10.3389/fimmu.2019.03150.
4. Fukumoto Y, Tanaka KF, Parajuli B, et al. Neuroprotective effects of microglial P2Y1 receptors against ischemic neuronal injury. J Cereb Blood Flow Metab. 2019; 39(11):2144-2156. doi:10.1177/0271678X18805317.
5. Morihara R, Yamashita T, Osakada Y, et al. Efficacy and safety of spot heating and ultrasound irradiation on in vitro and in vivo thrombolysis models. J Cereb Blood Flow Metab. 2022; 42(7):1322-1334. doi:10.1177/0271678X221079127.
6. Nosaka M, Ishida Y, Kimura A, et al. Contribution of the TNF-α (Tumor Necrosis Factor-α)-TNF-Rp55 (Tumor Necrosis Factor Receptor p55) Axis in the Resolution of Venous Thrombus. Arterioscler Thromb Vasc Biol. 2018; 38(11):2638-2650. doi:10.1161/ATVBAHA.118.311194.
7. Tanaka M, Ogaeri T, Samsonov M, et al. The 5α-Reductase Inhibitor Finasteride Exerts Neuroprotection Against Ischemic Brain Injury in Aged Male Rats. Transl Stroke Res. 2019; 10(1):67-77. doi:10.1007/s12975-018-0624-0.
8. Sakata Y, Yoshida C, Fujiki Y, et al. Effects of Casein Hydrolysate Ingestion on Thermoregulatory Responses in Healthy Adults during Exercise in Heated Conditions: A Randomized Crossover Trial. Nutrients. 2020; 12(3):867. doi:10.3390/nu12030867.

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