• Product Name: 37450/275 Tactile Measurement Kit (Von Frey)
• Order number: tlyon000418
• Brand Name: Ugo Italy

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37450/275- Tactile measurement kit (Von Frey)

The tactile measurement kit is composed of 20 nylon fiber filaments, known as Von Frey filaments or Semmes Weinstein monofilaments in English. It is mainly used to evaluate the tactile sensation of the skin and is a very popular non-invasive experimental equipment. It can provide a stimulation force of 0.008g-300g. The thickness and extension length of nylon thread determine the amount of stimulation provided. During the experiment, select a type of nylon filament according to the actual situation, adjust the appropriate extension length, and stimulate the skin vertically. By adjusting the elongation and replacing the nylon filament, the magnitude of the stimulation force can be adjusted. After the nylon filament is bent, continuous pushing will cause more bending, but the stimulating force will not increase again. When rodents receive sufficient mechanical stimulation, their claws will have a retraction reflex. The magnitude of the stimulation force is repeatedly adjusted, and the appropriate stimulation force is finally selected. Then, using the logarithmic formula of the stimulation force designed by "Semmes Weinstein", the 50% claw retraction threshold of the animal is calculated as an indicator for evaluating tactile testing. Von Frey tactile testing can be applied not only to the soles of the feet of mice and rats, but also widely used in clinical practice for tactile testing and high and low perception diagnosis.

In addition, an optional drilling worktable is available, with square holes made by laser cutting and punching, measuring 5 × 5mm in size²The distance between the holes is about 1mm, which is a comfortable environment for the test animals and also facilitates the operator to observe the plantar area of the animals. The drilling table is coated for easy cleaning and is not easily corroded Aesthesio ® Tactile sensory evaluation data chart

colour	Size	Item number	Target Stimulus (g)	Target Stimulus (mM)	Theoretical pressure Grams/Sq. mm	Hand foot back threshold	Plantarthreshold
green	1.65	514001	0.008	0.08	2.53	normal	normal
	2.36	514002	0.02	0.20	4.39	normal	normal
	2.44	514003	0.04	0.40	4.93	normal	normal
	2.83	514004	0.07	0.70	5.53	normal	normal
blue	3.22	514005	0.16	1.6	8.77	Reduce light touch	normal
	3.61	514006	0.40	3.9	16.1	Reduce light touch	Reduce light touch
Purple;	3.84	514007	0.60	5.9	18.4	Reduce light touch	Reduce light touch
	4.08	514008	1.0	9.8	24.4	Reduce light touch	Reduce light touch
	4.17	514009	1.4	13.7	27.9	Reduce light touch	Reduce light touch
	4.31	514010	2.0	19.6	27.4	Reduce light touch	Reduce light touch
red	4.56	514011	4.0	39.2	40.3	lose consciousness	Reduce light touch
	4.74	514012	6.0	58.8	52.6	lose consciousness	Reduce light touch
	4.93	514013	8.0	78.4	61.7

enclosure:

37450-278 animal cagesDrilling plateAnd bracket set

Attachment: Schematic diagram of perforated plate